August 1, 2024Applied PhycologyOpen Access

Antioxidant properties and bioactivity of three marine microalgae on human cancer cell lines

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Authors

HHHelen HerbertAtlantic University RPRachel ParkesBaylor College of Medicine MBMaria Elena BaroneUniversity of California, Santa Barbara

Discussion

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Implication

In vitro analysis demonstrates that Amphidinium carterae extracts inhibit human cancer cell proliferation, suggesting potential applications in multi-compound biorefineries.

Key Points

Amphidinium carterae extracts exhibit potent antioxidant capacity and suppress human cancer cell growth, whereas other tested microalgal species display no cytotoxic activity.
Growth of both A549 and MCF-7 carcinoma lines dropped below 4% at 25 to 100 µg ml−1, while antioxidant capacity reached up to 33.5 μmol Trolox equivalents per milligram.
Assessment using MTS assays and AO/PI staining evaluated solvent extracts across two cancer cell lines—preclinical in vitro models; further in vivo validation is required.

Cite This Study

Herbert et al. (2024) studied this question.

synapsesocial.com/papers/68e5dc63b6db643587572650 https://doi.org/10.1080/26388081.2024.2382146

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August 1, 2024Applied PhycologyOpen Access

Antioxidant properties and bioactivity of three marine microalgae on human cancer cell lines

View Full Paper

Ask AI

Bookmark

Authors

HHHelen HerbertAtlantic University RPRachel ParkesBaylor College of Medicine MBMaria Elena BaroneUniversity of California, Santa Barbara

Discussion

Member takes

Implication

In vitro analysis demonstrates that Amphidinium carterae extracts inhibit human cancer cell proliferation, suggesting potential applications in multi-compound biorefineries.

Key Points

Amphidinium carterae extracts exhibit potent antioxidant capacity and suppress human cancer cell growth, whereas other tested microalgal species display no cytotoxic activity.
Growth of both A549 and MCF-7 carcinoma lines dropped below 4% at 25 to 100 µg ml−1, while antioxidant capacity reached up to 33.5 μmol Trolox equivalents per milligram.
Assessment using MTS assays and AO/PI staining evaluated solvent extracts across two cancer cell lines—preclinical in vitro models; further in vivo validation is required.

Cite This Study

Herbert et al. (2024) studied this question.

synapsesocial.com/papers/68e5dc63b6db643587572650 https://doi.org/10.1080/26388081.2024.2382146

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