Sjogren's syndrome is a rare, chronic autoimmune disorder primarily marked by dry eyes and dry mouth due to the immune system targeting the lacrimal and salivary glands. It often coexists with other autoimmune conditions such as rheumatoid arthritis, systemic lupus erythematosus, or thyroiditis. The syndrome can also lead to renal issues, including interstitial nephritis and glomerulonephritis, along with distal or type 1 renal tubular acidosis, which can cause serious electrolyte imbalances Renal involvement is a wellrecognized extra-glandular manifestation of primary SS, occurring in 16%–67% of cases, with distal renal tubular acidosis (RTA) being common, reported in 4.3%–9% of PSS patients. . Here, we report the case of a 30-year-old woman with quadripar 4 esis. Her symptoms were traced back to type 1 renal tubular acidosis, which subsequently led to a diagnosis of Sjogren's syndrome. This case highlights a rare and challenging presentation of Sjogren's syndrome. The difculty in early detection and diagnosis is compounded by the current diagnostic criteria, often resulting in missed or delayed diagnose
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Srivani et al. (2024) studied this question.
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