Supplementary Figure S5 from Overexpression of an Engineered SERPINB9 Enhances Allogeneic T-cell Persistence and Efficacy

Supplementary Figure S5. Cytokine secretion profiles of CD30.CAR with 4-1BB spacer (CD30.bb) EBVSTs expressing different forms of SB9, in monoculture or after co-culture with KM-H2 tumor cells. A, Schematic of in vitro cytokine secretion assay where effector CD30.bb EBVSTs were either untreated and cultured in monoculture or co-cultured with KM-H2 tumor cells at a 1:1 ratio, in the absence of exogenous cytokines. B, Cytokine concentration measured from the supernatant of cells collected after 24 h in monoculture or co-culture.