Background: haemodialysis was the most common kidney replacement therapy. It was associated with both acute and chronic complications. Objectives To nd out the adverse events during the maintenance haemodialysis in chronic kidney disease patients. This observational study was done in 2023 among 160 patients undergoing maintenanc Material and Methods: e hemodialysis at Sri Venkateshwara Medical College Hospital and Research Institute, Pondicherry. The study was conducted after the approval of the Institutional Ethics Committee of Sri Venkateshwara Medical College Hospital and Research Institute, Pondicherry. The inclusion criteria were patients above the age of 18 years and End-stage renal disease patients undergoing maintenance hemodialysis at least twice a week. Informed consent was obtained from all the participants included in the study. 39% of the participants repor Results: ted having at least one complication. 31.6% had hypotension as a complication followed by 27.5% with muscle cramps. 12.2% had fever and chills and 10.2% had headache. 8.1% reported to have nausea and vomiting. Hypoglycaemia developed in 4.1% and hypertension in 3.1%. Chest pain was reported by 2.1% and catheter tip migration in 1.1%. Among those in whom hypotension was a complication, 67.7% had diabetes mellitus followed by 16.1% with chronic glomerulonephritis. Among those with muscle cramps, 63% had hypertension followed by 18.5% with diabetes. Four in ten Conclusion: who had undergone haemodialysis had at least one complication. The common complication is hypotension followed by muscle cramps,
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