CXCL12-loaded-hydrogel (CLG): A new device for metastatic circulating tumor cells (CTCs) capturing and characterization

Luigi Portella; Giulia Bertolini; Giuseppe Guardascione; Dario Guido Di Febbraro; Caterina Ieranò; Crescenzo D’Alterio; Giuseppina Rea; Maria Napolitano; Sara Santagata; Anna Maria Trotta; Rosa Camerlingo; Emilia Scarpa; Sabrina Chiara Cecere; Alessandro Ottaiano; Giuliano Palumbo; Alessandro Morabito; Teresa Somma; Giuseppe De Rosa; Laura Mayol; Roberto Pacelli; Sandro Pignata; Stefania Scala

doi:10.1016/j.heliyon.2024.e35524

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Abstract

Circulating Tumor Cells (CTCs) represent a small, heterogeneous population that comprise the minority of cells able to develop metastasis. To trap and characterize CTCs with metastatic attitude, a CXCL12-loaded hyaluronic-gel (CLG) was developed. CXCR4+cells with invasive capability would infiltrate CLG.

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Portella et al. (2024) studied this question.

synapsesocial.com/papers/68e5e5b8b6db643587579f7a https://doi.org/10.1016/j.heliyon.2024.e35524

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CXCL12-loaded-hydrogel (CLG): A new device for metastatic circulating tumor cells (CTCs) capturing and characterization

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Abstract

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CXCL12-loaded-hydrogel (CLG): A new device for metastatic circulating tumor cells (CTCs) capturing and characterization

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Abstract

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