Oculogyric crisis (OGC) is a form of acute dystonia with involuntary conjugated ocular gaze in a fixed position. Common causes include metabolic disorders and medications, primarily typical antipsychotics. A 24-year-old male with a history of persistent depressive disorder and possible bipolar disorder was admitted to the psychiatric unit due to suicidal ideation. He was started on aripiprazole 5 mg and subsequently increased to 10 mg due to uncontrolled mood disorder. The patient subsequently developed OGC, which resolved with benztropine and diphenhydramine. This case report highlights aripiprazole-induced OGC and prompt management with benztropine and first-generation antihistamines.
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Malik et al. (2024) studied this question.
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