Analysis of Haematological Parameters in Sickle Cell Trait and Sickle cell Disease patients of Chhattisgarh

In this study, we examined the hematological parameters between sickle cell disease, sickle cell trait and control individuals. Haematological parameters were compare among SS, AS and AA groups. However, significant difference were observed for HbF ((p<0.000), Hb ((p<0.000) HCT ((p<0.000), MCV ((p<0.000), except for MCH (P=0.757). Haematological parameters were comparable among male and female in study groups. However, no significant difference were observed excluding in SS patient for MCH ((p<0.035), in AS patients for Hb (p< =0.009) and in control (AA) for Hb ((p<0.001) and HCT ((p<0.007). HbF levels were higher in SS (19.39±7.14) patients than AS (1.06±0.74) and control (0.12±0.1). Highly significant difference for HbF level ((p<0.000) was observed among these study groups. Furthermore, diverse ranges of HbF levels were also noted in present study.