Acute kidney injury in severe alcohol-associated hepatitis treated with anakinra plus zinc or prednisone

Kavish R. Patidar; Wanzhu Tu; Thomas G. Cotter; Douglas A. Simonetto; Amon Asgharpour; Muhammad Y. Jan; Qing Tang; Yunpeng Yu; Yang Li; Moyinoluwa Taiwo; Prashanth Thevkar Nagesh; Srinivasan Dasarathy; Patrick S. Kamath; Craig J. McClain; Naga Chalasani; Gyöngyi Szabó; Ramón Bataller; Mack C. Mitchell; Wajahat Z. Mehal; Laura E. Nagy; Vijay H. Shah; Samer Gawrieh; Arun J. Sanyal

doi:10.1097/hep.0000000000001019

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Abstract

In a recent trial, patients with severe alcohol-associated hepatitis treated with anakinra plus zinc (A+Z) had lower survival and higher acute kidney injury (AKI) rates versus prednisone (PRED). We characterize the clinical factors and potential mechanisms associated with AKI development in that trial.

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Patidar et al. (2024) studied this question.

synapsesocial.com/papers/68e5fb6fb6db64358758f038 https://doi.org/10.1097/hep.0000000000001019

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Acute kidney injury in severe alcohol-associated hepatitis treated with anakinra plus zinc or prednisone

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Abstract

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Cite This Study

Acute kidney injury in severe alcohol-associated hepatitis treated with anakinra plus zinc or prednisone

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Abstract

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