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Nanobiomaterials demonstrate great potential in bone and dental tissue regeneration. These materials mimic the natural extracellular matrix in the human body, promoting the controlled release of growth factors and other bioactive molecules to enhance tissue regeneration and integration. Nanobioceramics mimic the structure and composition of natural bone. A major challenge in hard tissue healing is creating scaffolds that incorporate stem cells for bone tissue engineering. Scaffolds and implants for regenerative medicine should be designed using computer-aided design (CAD) and three-dimensional (3D) printing to replicate the tissue’s anatomical structure. Future studies should examine the relationship between the size of bioceramics and biological reactions. The more interacting nature of nanoceramics better triggers the cellular processes, facilitating the regeneration of calcified tissue. Osteoblasts and osteoclasts are crucial in the development and maintenance of calcified tissue in vivo, and nanoceramics enhance the functionality of orthopedic and dental implants.
Kirubanandan Shanmugam (Thu,) studied this question.