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Extrahepatic metastasis of hepatocellular carcinoma (HCC) is a sign of advanced disease with poor prognosis. Haematogenous metastasis to the urinary bladder is extremely rare. We describe a case of a 66-year-old male with advanced HCC that developed HCC metastasis to the bladder. There have only been six case reports previously documenting this. Uniquely this is the first case to develop metastatic disease to the bladder after receiving both locoregional and systemic therapy.
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Lorger et al. (2024) studied this question.
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