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Case report demonstrates papillary thyroid carcinoma with neck metastasis in a patient with Graves disease, highlighting that hyperfunctioning thyroid nodules may harbor malignancy.
Hyperfunctioning (hot) nodules are considered benign while cold nodules are associated with a higher risk of thyroid cancer. In this case report, we present a patient diagnosed with Graves' disease and later found to have papillary thyroid carcinoma (Bethesda VI), confirmed by fine needle aspiration (FNA) biopsy, with regional metastasis to the neck and possible metastasis to the lungs. This paper demonstrates that hot nodules are not always benign, and could be associated with malignancy.
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Jamal et al. (2024) studied this question.
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