CLEAR Thrombectomy Score: An Index to Estimate the Probability of Good Functional Outcome With or Without Endovascular Treatment in the Late Window for Anterior Circulation Occlusion

James E. Siegler; Manisha Koneru; Muhammad M. Qureshi; Mohamed Doheim; Raul G. Nogueira; Nicolas Martinez‐Majander; Simon Nagel; Mary Penckofer; Jelle Demeestere; Volker Puetz; Marc Ribó; Mohamad Abdalkader; João Pedro Marto; Alhamza R Al‐Bayati; Hiroshi Yamagami; Diogo C Haussen; Marta Olivé‐Gadea; Simon Winzer; Mahmoud Mohammaden; Robin Lemmens; Kanta Tanaka; Pekka Virtanen; Anne Dusart; Flavio Bellante; Daniel Kaiser; François Caparros; Hilde Hénon; João Nuno Ramos; Santiago Ortega‐Gutiérrez; Sunil A. Sheth; Stefania Nannoni; Lieselotte Vandewalle; Johannes Kaesmacher; Sergio Salazar‐Marioni; Liisa Tomppo; Rita Ventura; Syed Zaidi; Mouhammad Jumaa; Alicia C. Castonguay; Milagros Galecio‐Castillo; Ajit S Puri; Adnan Mujanović; Piers Klein; Liqi Shu; Behzad Farzin; Hannah Moomey; Hesham Masoud; Jessica Jesser; Markus Möhlenbruch; Peter A. Ringleb; Daniel Strbian; Osama O. Zaidat; Shadi Yaghi; Davide Strambo; Patrik Michel; Daniel Roy; Shinichi Yoshimura; Kazutaka Uchida; Jean Raymond; Thanh N. Nguyen

doi:10.1161/jaha.124.034948

July 9, 2024Journal of the American Heart AssociationOpen Access

CLEAR Thrombectomy Score: An Index to Estimate the Probability of Good Functional Outcome With or Without Endovascular Treatment in the Late Window for Anterior Circulation Occlusion

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Key Points

Derivation of the CLEAR thrombectomy score aims to identify patients who achieve favorable functional outcomes with intervention rather than standard medical therapy.
Targeting the extended therapeutic window of 6 to 24 hours after last known well, the index estimates functional recovery for anterior circulation occlusion.
This scoring approach supports clinical decisions between endovascular therapy and best medical management, optimizing treatment choices across extended presentation windows.

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Implication

Derives a predictive score for favorable functional outcomes following endovascular therapy in late-window anterior stroke, highlighting treatment selection beyond standard timeframes.

Abstract

With the expanding eligibility for endovascular therapy (EVT) of patients presenting in the late window (6-24 hours after last known well), we aimed to derive a score to predict favorable outcomes associated with EVT versus best medical management.

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Siegler et al. (2024) studied this question.

synapsesocial.com/papers/68e60e3db6db6435875a0c37 https://doi.org/10.1161/jaha.124.034948

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CLEAR Thrombectomy Score: An Index to Estimate the Probability of Good Functional Outcome With or Without Endovascular Treatment in the Late Window for Anterior Circulation Occlusion

Key Points

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Implication

Abstract

Discussion

Cite This Study

CLEAR Thrombectomy Score: An Index to Estimate the Probability of Good Functional Outcome With or Without Endovascular Treatment in the Late Window for Anterior Circulation Occlusion

Key Points

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Implication

Abstract

Discussion

Cite This Study

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