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July 8, 2024Organic LettersOpen Access

Telescoping a Prenyltransferase and a Diterpene Synthase to Transform Unnatural FPP Derivatives to Diterpenoids

Henry Struwe Heng Li Finn Schrödter Laurent Höft Jörg Fohrer Jeroen S. Dickschat Andreas Kirschning

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Abstract

New diterpenoids are accessible from non-natural FPP derivatives as substrates for an enzymatic elongation cyclization cascade using the geranylgeranyl pyrophosphate synthase (GGPPS) from

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Cite This Study

Struwe et al. (2024) studied this question.

synapsesocial.com/papers/68e6107ab6db6435875a301f https://doi.org/10.1021/acs.orglett.4c01670

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