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Literature synthesis reveals multiple maternal and environmental risk factors for autism spectrum disorder in offspring, highlighting critical windows in prenatal neurodevelopment.
Autism spectrum disorder is caused by a variety of determinants. This study focuses on how the mother’s exposure to pesticides, ozone pollution, and infections, as well as the mother’s pre-existing disorders, including diabetes and preeclampsia, result in the development of autism spectrum disorder in the child. It also examines the role that maternal immune activation and autoantibodies have on the risk of ASD in the mother’s offspring. In addition, it analyzes specific circumstances during childbirth, which include maternal hemorrhage and the use of forceps, and addresses their potential impacts on the risk of autism in the child. Lastly, this study describes the association between incorrect brain development and ASD. Along with compiling the several different maternal circumstances during pregnancy that could cause autism, this study also mentions the link between early brain overgrowth and ASD. Essentially, it clears up any confusion about specific conjectures regarding possible maternal factors that contribute to autism spectrum disorder by presenting the data in a clear and organized manner.
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Mila Sonkin (2024) studied this question.
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