July 3, 2024Current Analytical Chemistry

Fast Determination of Fat-soluble Vitamins in Pharmaceutical Preparations by High-Performance Liquid Chromatography

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GKGamze Ergin KızılçayIstanbul University SÇSena Çağlar-AndacTürkisch-Deutsche Universität STSıdıka Ertürk TokerFatih University

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Implication

Analytical method validation demonstrates rapid quantification of fat-soluble vitamins in syrups and tablets, highlighting robust quality control for pharmaceuticals.

Key Points

Simultaneous determination of fat-soluble vitamins A, D3, E, and K1 is achieved in syrup and tablet pharmaceuticals using a rapid normal-phase HPLC assay.
Limit of detection values reach 0.040 μg ml-1 for vitamin K1, while relative standard deviation repeatability metrics remain strictly below 2.54% across runs.
High-performance liquid chromatography on a cyano column under ICH guidelines demonstrates high recovery, enabling reliable quality control of pharmaceutical syrups.

Cite This Study

Kızılçay et al. (2024) studied this question.

synapsesocial.com/papers/68e61918b6db6435875abb0e https://doi.org/10.2174/0115734110314921240622111849

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Implication

Analytical method validation demonstrates rapid quantification of fat-soluble vitamins in syrups and tablets, highlighting robust quality control for pharmaceuticals.

Fast Determination of Fat-soluble Vitamins in Pharmaceutical Preparations by High-Performance Liquid Chromatography

Discussion

Member takes

Implication

Key Points

Cite This Study

Fast Determination of Fat-soluble Vitamins in Pharmaceutical Preparations by High-Performance Liquid Chromatography

Discussion

Member takes

Implication

Key Points

Cite This Study

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Also Consider