Phytomediated fabrication of silver nanoparticles using Syzygium cumini L. aqueous leaf extract and evaluation of their antioxidant potential

Plant leaf extracts are a rich source of phytochemicals like polyphenols, flavonoids, and sugars that will serve as reducing, capping, and stabilising agents while reducing silver ions to silver, Syzygium cumini L. aqueous leaf extract was used to create silver nanoparticles (AgNPs).These phytochemicals were quantified in an aqueous leaf extract, and their potential to mediate AgNP biosynthesis was then assessed.Using UVvisible spectroscopy, a particle size analyzer (PSA), FTIR (fourier transform infrared spectroscopy), FESEM (field emission scanning electron microscopy), and HRTEM (high-resolution transmission electron microscopy), the optical, structural, and morphological characteristics of biosynthesized AgNPs were assessed.HRTEM analysis revealed the formation of AgNPs with a spherical shape and an average diameter of 15 nm.Using 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, antioxidant potential was evaluated, biosynthesized AgNPs demonstrated increased antioxidant efficacy with IC 50 = 17.02 µg/ml compared to leaf extract with IC 50 = 21.09µg/ml.With the phosphomolybdenum assay, the AgNPs (74.26 mg AAE/g) showed higher total antioxidant capacity than the aqueous leaf extract (53.61 mg AAE/g) at a concentration of 100 µg/ml.Based on current research, AgNPs may prove as a potent antioxidant agent which enhances their biomedical applications in future.