The chemoprofile of willow bark (Salix cortex) for pharmaceutical use was investigated using a combination of in vitro bioassays and analytical techniques. Salicylates were isolated by means of (semi‐)preparative HPLC, and their structure was elucidated by means of LC‐MS and 1D/2D‐NMR experiments. Bioactivity assays identified key compounds of selected Salix extracts contributing to the overall anti‐inflammatory potential. Finally, these phytochemicals were mapped quantitatively by means of LC‐MS/MS.
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Antoniadou et al. (2024) studied this question.
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