Evaluation of the role of neoadjuvant chemotherapy in the management of rectal cancer

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Efficacy and safety of neoadjuvant chemoradiotherapy versus chemotherapy alone in locally advanced rectal cancer2025
2. 2Neoadjuvant Therapy in Locally Advanced Rectal Cancer—What Result Should We Expect?2026
3. 3Combination of neoadjuvant and adjuvant chemotherapy with FOLFOX compared with adjuvant chemotherapy in management of locally advanced rectal cancers: a randomized trial of a promising therapeutic approach2024 · 4 citations
4. 4Total Neoadjuvant Therapy with Induction FOLFIRINOX and Concurrent Chemoradiation for Locally Advanced Lower-Middle Rectal Cancer: A retrospective study in Vietnam2025
5. 5Neoadjuvant Chemotherapy Without Radiation for Locally Advanced Rectal Cancer: A Meta-analysis of Surgical Outcomes After Total Mesorectal Excision2025 · 5 citations