Pancreatic Cancer Accompanied by a Moderate-Sized Pseudocyst

Pancreatic cancer presenting concurrently with a moderate-sized pseudocyst is a clinical rarity that poses signicant diagnostic challenges. The presence of a pseudocyst can often obscure the underlying pancreatic parenchyma, complicating the preoperative identication of malignancies through imaging. Despite considerable advancements in diagnostic imaging technologies, there remains a notable difculty in distinguishing cystic pancreatic lesions from pancreatic adenocarcinoma prior to surgery. This case report details the clinical journey of a 61-year-old female who exhibited symptoms such as epigastric pain, vomiting, constipation, and jaundice, without a prior history of alcohol use or pancreatitis. Diagnostic modalities, including ultrasonography, endoscopy, and contrastenhanced computed tomography (CECT), were employed, revealing a periampullary mass and subsequent biopsy conrmed moderately differentiated adenocarcinoma. Challenges arose due to the pseudocyst's compression on the pancreatic tissue, which initially disguised the malignant nature of the underlying lesion. The complex interplay between the pseudocyst and the carcinoma underscored the necessity for meticulous diagnostic scrutiny and strategic surgical planning. The ndings from this case emphasize the need for heightened clinical vigilance and a comprehensive approach in the evaluation of pancreatic lesions, particularly when classical symptoms of pancreatic pathology are accompanied by cystic abdominal structures.