1092 Perioperative Practices and Early Post-Transplant Outcomes in Deceased Donor Simultaneous Kidney Pancreas Transplants (SPK): Results of a National Transplant Access to Theatre (NTACT) Audit

Aim Deceased donor simultaneous kidney-pancreas transplants (SPK) outcomes hinge on donor and recipient factors. Limited UK data on perioperative practices and outcomes prompted the National Transplant Access to Theatre (NTACT) study, aiming to unveil the current landscape. Method A prospective audit covered adult deceased donor kidney-only transplants in five UK centres from February to September 2022. RedCap recorded data and analysed descriptively. Results Among 29 SPK transplants, 24 were analysed. Preoperative antibiotics were universal, and consultant surgeons led all operations, though only 62.5% were directed by consultant anaesthetists. Central and arterial lines were standard, with 42% using advanced hemodynamic monitoring. Goal-directed fluid therapy, done using static parameters in 62.5% of cases, was common. Post-operatively, 75% were routed to the Intensive Care Unit. Encouragingly, 30-day mortality was 0%, and primary graft function rates were 83% for kidneys, 92% for pancreas. The median hospital stay was 12 days (IQR: 11-18), with a 29% readmission rate and 33% re-operation rate. Notably, readmission rates differed between Donation after Circulatory Death (DCD) and Donation after Brain Death (DBD) organs (17% vs. 41%). Conclusions Diverse perioperative practices and notable early complications were observed. While limited sample size precludes statistical associations, this underscores the need for future, more extensive studies.