Associations between polymorphisms of the UCP2 gene with milk production traits in dairy cattle

The conducted research aimed to estimate the associations between four polymorphisms (rs133711548, rs461080303, rs434063643, rs464399127) in the UCP2 gene and the selected milk production traits (milk, protein, fat yield, and protein, as well as fat content). The study included 446 Holstein cows. The genotypes of individual animals were determined using the ACRS and PCR-RFLP methods. The frequency of the most common alleles was as follows: rs133711548: C – 0.72, rs461080303: C – 0.59, rs434063643: T – 0.69 and rs464399127: G – 0.71. In the conducted research, statistically significant differences (P≤0.05; P≤0.01) were found between individual genotypes of the studied SNPs and milk yield, protein, and fat yield.