In patients with normal heart and normal conduction system, the initial depolarized segment in ventricle is interventricular septum which begins with septal fascicle of the left bundle branch from left side and direction to right side followed by a simultaneous depolarization of the remaining ventricular free walls from endocardium to pericardium via the right and left bundle branches. But among patients with left bundle branch block (LBBB), the initial septal activation is changing direction and become from right to left then the left ventricular activation is delayed, ST segment and T wave abnormalities occur, and septal Q waves indicative of an MI are absent in this condition. About 0.5 percent of patients with acute myocardial infarction had left bundle-branch block. Because this changes the patients with left bundle branch block (LBBB) and acute myocardial infarction (MI) is challenge to the clinician. The diagnosis of MI with electrocardiogram (ECG) is so difficult in the setting of LBBB because of the characteristic ECG changes caused by altered interventricular septal and left ventricle free wall depolarization. Here we review the ECG diagnostic criteria included all criteria until now and short summary of patient with acute MI and LBBB condition.
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Mohammed Habib (2024) studied this question.
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