June 27, 2024ScienceOpen Access

Homeocurvature adaptation of phospholipids to pressure in deep-sea invertebrates

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Authors

JWJacob R. WinnikoffHarvard University DMDaniel MilshteynUC San Diego Health System SUS. UrbanoUniversity of Delaware

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Implication

Structural analysis reveals homeocurvature adaptation of phospholipids in deep-sea ctenophores, indicating how nonbilayer membrane phases modulate biological pressure tolerance.

Key Points

Deep-sea ctenophores achieve pressure tolerance through homeocurvature adaptation, relying on plasmalogens to maintain membrane organization under hydrostatic pressure.
Structural analysis and lipidomics reveal that phospholipids with strong negative spontaneous curvature form nonbilayer phases under elevated hydrostatic pressure.
These structural lipid behaviors explain how hydrostatic pressure tolerance is conferred, highlighting molecular adaptations that constrain depth ranges in marine organisms.

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Winnikoff et al. (2024) studied this question.

synapsesocial.com/papers/68e62ea5b6db6435875c13f5 https://doi.org/10.1126/science.adm7607

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Implication

Structural analysis reveals homeocurvature adaptation of phospholipids in deep-sea ctenophores, indicating how nonbilayer membrane phases modulate biological pressure tolerance.

Homeocurvature adaptation of phospholipids to pressure in deep-sea invertebrates

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Implication

Key Points

Cite This Study

Homeocurvature adaptation of phospholipids to pressure in deep-sea invertebrates

Discussion

Member takes

Implication

Key Points

Cite This Study

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