Supplementary Figure 3 from Transcriptome Deconvolution Reveals Absence of Cancer Cell Expression Signature in Immune Checkpoint Blockade Response

Yu Amanda Guo; Tanmay Kulshrestha; Mei Mei Chang; Irfahan Kassam; Egor Revkov; Simone Rizzetto; Aaron C. Tan; Daniel S.W. Tan; Iain Beehuat Tan; Anders J. Skanderup

doi:10.1158/2767-9764.26106970.v1

June 26, 2024Open Access

Supplementary Figure 3 from Transcriptome Deconvolution Reveals Absence of Cancer Cell Expression Signature in Immune Checkpoint Blockade Response

View Full Paper

Ask AI

Bookmark

Share

Key Points

Gene expression differences distinguish responders from non-responders across discovery cohorts, lacking a distinct cancer cell expression signature.
Transcriptome deconvolution across patient discovery cohorts pinpoints reproducible gene profiles associated with immune checkpoint blockade outcomes.
Identification of shared immune checkpoint blockade expression patterns highlights clinical response markers, supporting tailored immunotherapy strategies.

Implication

Transcriptomic analysis reveals differentially expressed genes across discovery cohorts, highlighting biomarkers of immune checkpoint blockade response.

Abstract

No abstract yet. The journal hasn't published one we can show.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Guo et al. (2024) studied this question.

synapsesocial.com/papers/68e633b3b6db6435875c5917 https://doi.org/10.1158/2767-9764.26106970.v1

View Full Paper

Ask AI

Bookmark

Share

Supplementary Figure 3 from Transcriptome Deconvolution Reveals Absence of Cancer Cell Expression Signature in Immune Checkpoint Blockade Response

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplementary Figure 3 from Transcriptome Deconvolution Reveals Absence of Cancer Cell Expression Signature in Immune Checkpoint Blockade Response

Key Points

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading