Sphenoclival extramedullary prasmocytomas are a rare disease. We present a 58-year-old patient with headache, ophthalmoparesis and ptosis of the right eyelid, symptoms dating back for 2-3 weeks. Brain MRI with contrast revealed clivus involvement by an irregularly shaped soft tissue tumor with a heterogeneous structure. Biopsy confirmed the diagnosis of solitary plasmacytoma after ruling out systemic spread by the initial assessment. The patient conducted definitive intensity modulated radiation therapy (IMRT) in the tumor area up to total dose 50 Gy with dayli dose 2 Gy. Through this rare clinical case, we want to show the difficult pathohistological and differential diagnosis, as well as the need for IMRT, since it is a radiosensitive tumor.
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