Multiple Nasal Swellings and An Unusual Diagnosis: Extramedullary Plasmacytoma

Plasmacytomas are lymphoproliferative disorders characterized by monoclonal proliferation of plasma cells.Of these extramedullary plasmacytomas are rare tumors.They are mostly seen in the submucosa of the upper aerodigestive tract.Clinical manifestations vary depending on the location of the lesions.In the nasal cavity, it can cause nasal obstruction, anosmia/hyposmia, headache and epistaxis.The risk of conversion to multiple myeloma is 15%-20%.To rule out multiple myeloma, a complete systemic evaluation should be done in all patients with extramedullary plasmacytoma.Excision biopsy/IHC play an important role in differentiating and planning the management of these disorders.It is a highly radiosensitive tumor, so radiotherapy is the treatment of choice.We report a case of a 38 years old female presented to ENT department with nose block and diagnosed as extramedullary plasmacytoma without any systemic manifestation and no evidence of multiple myeloma, treated with surgery as sole modality of treatment and no recurrences on follow up to date, which makes this case different from others.Even though radiotherapy is the treatment of choice, it can be treated with surgery alone if the lesion is small in size.Keeping the recurrence rates in mind, regular follow ups are required for early detection and treatment.