Extramedullary Plasmacytoma of the Larynx : A Case Report

Plasmacytoma is a neoplastic proliferation of plasma cells, a terminally differentiated type of B lymphocytes. Extramedullary plasmacytoma, which occurs outside the bone marrow, is a relatively rare disease. It is most commonly found in the head and neck regions, particularly in the sinonasal cavity. However, plasmacytoma rarely occurs in the larynx. In this report, we describe a case of extramedullary plasmacytoma in the supraglottis. A biopsy was performed to confirm the diagnosis. The patient with extramedullary plasmacytoma in the larynx was treated with radiation therapy and achieved reasonable local control without subsequent progression to multiple myeloma. Radiation therapy is the preferred treatment for localized extramedullary plasmacytoma. It is essential to select the appropriate treatment based on the site of occurrence, the patient's medical history, and the degree of tumor progression.