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June 24, 2024CirculationOpen Access

Impaired Intracellular Calcium Buffering Contributes to the Arrhythmogenic Substrate in Atrial Myocytes From Patients With Atrial Fibrillation

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Abstract

Alterations in the buffering of intracellular Ca

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Fakuade et al. (2024) studied this question.

synapsesocial.com/papers/68e637ebb6db6435875c9641 https://doi.org/10.1161/circulationaha.123.066577

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Calcium Buffering in the Heart in Health and Diseasereview · 2019 · 96 citations
2Tachycardia-induced silencing of subcellular Ca2+ signaling in atrial myocytespreclinical · 2014 · 116 citations
3Atrial Fibrillation Is Associated With Increased Spontaneous Calcium Release From the Sarcoplasmic Reticulum in Human Atrial MyocytesOriginal Research · 2004 · 359 citations
4The ryanodine receptor channel as a molecular motif in atrial fibrillation: pathophysiological and therapeutic implicationsreview · 2010 · 125 citations
5Ryanodine receptor cluster fragmentation and redistribution in persistent atrial fibrillation enhance calcium releaseOriginal Research · 2015 · 114 citations