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June 24, 2024British Journal of Dermatology

High-dose vitamin D supplementation does not improve outcome in a cutaneous melanoma population: results of a randomized double-blind placebo-controlled study (ViDMe trial)

Julie De Smedt Sofie Van Kelst Laudine Janssen Vivien Marasigan Veerle Boecxstaens Kris Bogaerts Ann Belmans Dirk Vanderschueren Katleen Vandenberghe Oliver Bechter Claudia Aura Diether Lambrechts Tinne Strobbe Gabriella Emri Arjen Nikkels Marjan Garmyn

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Abstract

Observational studies in cutaneous melanoma (CM) have indicated an inverse relationship between levels of 25-hydroxyvitamin D and Breslow thickness, in addition to a protective effect of high 25-hydroxyvitamin D levels on clinical outcome.

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Cite This Study

Smedt et al. (2024) studied this question.

synapsesocial.com/papers/68e637feb6db6435875c9bb1 https://doi.org/10.1093/bjd/ljae257

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Serum 25-Hydroxyvitamin D <sub>3</sub> Levels Are Associated With Breslow Thickness at Presentation and Survival From MelanomaRetrospective Study · 2009 · 295 citations
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3Prognostic Value of Baseline Serum 25-Hydroxyvitamin D in High-Risk Resected Cutaneous MelanomaCohort Study · 2026
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5Vitamin D in Melanoma: Potential Role of Cytochrome P450 Enzymes2024 · 7 citations