Secondary radiation-induced angiosarcoma of the breast in a patient with a history of infiltrating ductal carcinoma: a case report

Angiosarcoma of the breast is a rare cancer, and there are two forms of presentation: the primary, where no identifiable precursor factors are associated, and the secondary, associated with radiotherapy.We report a case of a woman who developed a primary lesion 4 years after completing adjuvant radiotherapy for an infiltrating ductal carcinoma of the breast.She was conservatively treated with radical locoregional management, resulting in no residual disease; however, she exhibited a rapid tendency to systemic relapse, with conventional aromatase inhibitors proving to be ineffective.The treatment of choice is surgical, with which prolonged survival is sometimes achieved after complete resections.