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June 20, 2024Saudi Journal of Biological SciencesOpen Access

Gene-gene and gene-environmental interaction of dopaminergic system genes in Pakistani children with attention deficit hyperactivity disorder

Moin Ahmed Ansari Habib Ahmed Naqvi Feriha Fatima Khidri Aatir H. Rajput Ambar Mahmood Ali Muhammad Waryah

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Abstract

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder influenced by genetic and environmental factors. This study examined the specific gene variants, dopamine transporter 1 (DAT1) rs6350, dopamine receptor D3 (DRD3) rs6280, dopamine receptor D2 (DRD2) rs6277, and catechol-O-methyltransferase (COMT) rs4633, in relation to ADHD among Pakistani children by exploring the potential gene-gene and gene-environment interactions.

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Ansari et al. (2024) studied this question.

synapsesocial.com/papers/68e63f56b6db6435875d0886 https://doi.org/10.1016/j.sjbs.2024.104045

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