High mortality and complications in patients admitted with Takotsubo cardiomyopathy without improvement in outcomes over the years.

Abstract Introduction Takotsubo cardiomyopathy continues to be a major cause of mortality and morbidity. The goal of this study was to evaluate the outcome data of patients with Takotsubo cardiomyopathy using a large inpatient database. Methods We used the Nationwide inpatient sample (NIS) database for our study. We evaluated trends, mortality, and complications of patients admitted with Takotsubo cardiomyopathy from available 2016-2020 years in adults over the age of 18. Results A total of 199,890 patients with Takotsubo were found in our database with 83% being female and higher prevalence with age, Caucasian race, and highest income. Mortality was high at 6.5 % with no significant improvement over the years studied. Furthermore, major complications were substantial. Cardiogenic shock occurred in 6.6%, atrial fibrillation in 20.7%, Cardiac arrest in 3.4%, congestive heart failure in 35.9% and stroke in 5.3%. Conclusion Takotsubo cardiomyopathy is associated with high mortality and complications with no improvement in outcome over the 5 years study. Further improvement in care is needed to improve outcomes.