Severe Vitamin A Deficiency and Xerophthalmia Leading to Corneal Perforation

Purpose: To highlight the ocular manifestations and complications of severe vitamin A deficiency Observations: A 42-year-old female with history of alcoholism presented with severe malnutrition and vitamin A deficiency, xerosis, and optic neuropathy, which was complicated by corneal perforation. Conclusions: This case highlights the importance of considering nutritional deficiencies in patients presenting with chronic visual symptoms. The potential for severe vitamin A deficiency to induce corneal perforation necessitates its consideration in patients harboring risk factors such as alcoholism, inadequate nutritional intake, and conditions associated with malabsorption.