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Supplementary Figure 7: Gut Microbiome Changes in Partners of Bladder Cancer Patients A: Stacked bar chart representing the relative abundances of key bacterial genera before, during, and after the chemotherapy periods in partners of patients. B: Principal Coordinates Analysis (PCoA) plot based on weighted UniFrac distances showing the clustering of microbiome samples at different stages of chemotherapy (before, during, after). The ellipses represent the 95% confidence intervals for each group. C: Violin plots illustrating the distribution of alpha diversity indices (ACE, Chao1, Observed, Pielou, Shannon, Simpson) at three key stages of chemotherapy. D: Bar graph depicting the percentage representation of selected bacterial genera across the three phases of chemotherapy in partners. E: Linear Discriminant Analysis (LDA) effect size (LEfSe) plot comparing bacterial taxa before and after chemotherapy, identifying which taxa are statistically significantly different between the two time points. F: Venn diagram illustrating the unique and shared bacterial taxa found at each phase of chemotherapy.
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Bukavina et al. (2024) studied this question.
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