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June 16, 2024Journal of Clinical InvestigationOpen Access

HIF-2α expression and metabolic signaling require ACSS2 in clear cell renal cell carcinoma

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Authors

ZBZachary A. BacigalupaEAEmily N. ArnerLVLogan M. Vlach

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Cite This Study

Bacigalupa et al. (2024) studied this question.

synapsesocial.com/papers/68e64877b6db6435875d96e4https://doi.org/10.1172/jci164249
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ACSS2 enables melanoma cell survival and tumor metastasis by negatively regulating the Hippo pathway2024 · 1 citations
  2. 2Targeting ACSS2 activity suspends the formation of chemoresistance through suppressed histone H3 acetylation in human breast cancer2024 · 1 citations
  3. 3Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress2015 · 837 citations
  4. 4SREBF2 enhances lipid metabolism and represses anti-tumor immune responses in cervical cancer by increasing ACAT22026 · 1 citations
  5. 5Acetyl-CoA synthetase 2 contributes to a better prognosis for liver cancer by switching acetate-glucose metabolism2024 · 6 citations