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Adrenal adenoma are usually benign neoplasms arising from the cortex of adrenal gland. Most adenomas do not produce hormones, but can produce excessive amounts of adrenocortical hormones. However, cases have been described when these types of tumors produce catecholamines, which are characterized by cardiotoxicity. Most studies have focused on adrenal medulla tumors that develop as a result of degeneration of chromaffin cells and neuros. Most of them synthesize and secrete catecholamines. This case of adrenal cortical adenoma discussed above is a functional tumor, the chronic hormonal activity of which was manifested by hypertrophy of cardiomyocytes, the formation of infarction, which led us to the final result, called heart rupture.
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Latchkepiani et al. (2024) studied this question.
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