Radical adrenalectomy in a 10-year-old with functional adrenal adenoma and severe heart failure normalized LVEF from 17% to 55% over one year, showing reversibility.
Demonstrates that severe dilated cardiomyopathy and heart failure secondary to a functional adrenal adenoma in a child can be fully reversed following surgical resection.
Absolute Event Rate: 0% vs 0%
Abstract Background Functional adrenal adenoma is uncommon in children, and cardiovascular complications, such as dilated cardiomyopathy and heart failure (HF), are rare as initial manifestations. Case summary Here, we report a 10-year-old girl presenting with acute HF, mild troponin rise and severe left ventricular dysfunction in echocardiography. The CMR demonstrated dilated cardiomyopathy (LVEF=17%) with concentric LVH and a focal myocardial infarction. Extracardiac findings in CMR showed an incidental 3-cm right adrenal mass, and subsequent dedicated MRI with adrenal protocol showed features of a benign adenoma. Laboratory findings showed mixed Cushing's and hyperaldosteronism suggestive of a functional adrenal adenoma. The radical right adrenalectomy was performed, and pathology confirmed the diagnosis. Discussion In the one-year follow-up echocardiography, the LVEF was back to normal (LVED 55%), highlighting the reversible nature of cardiomyopathy in this condition.
Eini et al. (Fri,) reported a other. Radical adrenalectomy in a 10-year-old with functional adrenal adenoma and severe heart failure normalized LVEF from 17% to 55% over one year, showing reversibility.
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