Listeriosis in the Krasnoyarsk Krai (Russian Federation): Case Report Study

Background. Official statistics on the incidence of listeriosis does not reflect its real incidence rate, despite the increase in registered cases of the disease in various regions of Russia. The aim of the study. To draw attention to the diagnosis of listeriosis, especially in maternity institutions. Materials and methods. We conducted a descriptive study of 8 patients with listeriosis (7 adults, 1 child), registered in 2022–2023 in Krasnoyarsk regional hospitals. Bacteriological testing was carried out in the laboratories of hospi-tals where the patients were treated. Identification of isolated bacteria was carried out using the Maldi-Tof method on Vitec MS (BioMerieux, France) and Microflex (Bruker, Germany) mass spectrometers. Description of clinical cases. In 2022–2023, in the Krasnoyarsk Krai, for the first time in the last 10 years, 8 cases of listeriosis were registered (7 women, 1 child). 5 women were admitted to the infectious diseases department after pre-mature complicated labor, including 4 cases of cesarean section. All children were born with congenital disorders of varying severity. One child died on the second day after birth. Two cases are not associated with pregnancy – acute appendicitis and bacterial meningitis. All adults were hospitalized for a medical emergency. The results of bacteriological examination were crucial for making a diagnosis. The incidence of listeriosis was 0.15 per 100 thousand population of the region and 0.84–0.98 per 1000 postpartum women and patients in the infectious diseases department. Conclusion. The described cases confirm the relevance of using modern methods of laboratory diagnosis of listeri-osis and infection control, especially in obstetric medical insitutions.