Case report demonstrates severe vitamin B12 deficiency mimicking thrombotic microangiopathy in a 53-year-old female, highlighting the need to test vitamin levels to prevent misdiagnosis.
Key Points
Severe vitamin B12 deficiency induced pancytopenia and hemolysis with circulating schistocytes, mimicking microangiopathic hemolytic anemia in a 53-year-old female patient.
Case report investigation of a 53-year-old female presenting with jaundice and diarrhea confirmed pernicious anemia through bone marrow biopsy and serum vitamin B12 testing.
Early recognition of megaloblastic changes enables rapid symptom resolution with parenteral vitamin B12 supplementation, avoiding unnecessary and invasive plasma therapies.