June 4, 2024Microbiology SpectrumOpen Access

A comparative evaluation of five phenotypic methods for identification of carbapenemase-producing Enterobacteriaceae: a modified carbapenemase detection test

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Authors

HSHamid SolgiIsfahan University of Medical Sciences ABAli BadamchiChildren's Medical Center FSFereshteh ShahcheraghiPasteur Institute of Iran

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Implication

Comparative evaluation demonstrates high sensitivity for a modified-Carba NP test in Enterobacteriaceae isolates, highlighting its utility as a rapid screening tool.

Key Points

Modified-Carba NP testing reliably identifies carbapenemase production in Enterobacteriaceae, demonstrating superior sensitivity over other phenotypic methods.
The modified-Carba NP test achieved 95.06% sensitivity and 94.44% specificity, outperforming the in-house assay while misidentifying select OXA-48 isolates.
Evaluation of five phenotypic methods highlights modified-Carba NP as a simple screening test, supporting rapid detection and surveillance of resistant pathogens.

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Solgi et al. (2024) studied this question.

synapsesocial.com/papers/68e6635ab6db6435875eff0a https://doi.org/10.1128/spectrum.00386-24

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Implication

Comparative evaluation demonstrates high sensitivity for a modified-Carba NP test in Enterobacteriaceae isolates, highlighting its utility as a rapid screening tool.

A comparative evaluation of five phenotypic methods for identification of carbapenemase-producing Enterobacteriaceae: a modified carbapenemase detection test

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Implication

Key Points

Cite This Study

A comparative evaluation of five phenotypic methods for identification of carbapenemase-producing Enterobacteriaceae: a modified carbapenemase detection test

Discussion

Member takes

Implication

Key Points

Cite This Study

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