What does this research mean for the field?

The resaCPE test detects carbapenemase-producing Enterobacterales with a sensitivity of 98.7% and provides results within 3.5 hours, making it a rapid and low-cost alternative for primary screening. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to develop a rapid and low-cost detection method for carbapenemase-producing Enterobacterales.

March 1, 2026Journal of Clinical MicrobiologyOpen Access

resaCPE: a rapid, low-cost colorimetric assay for the detection of carbapenemase-producing Enterobacterales

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Authors

MJMitchell A JeffsQueen's University GCGabhan ChalmersUniversity of Guelph HWHenry WongQueen's University

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Implication

Develops a rapid colorimetric assay to detect carbapenemase-producing Enterobacterales, suggesting it could improve infection control in healthcare.

Key Points

The aim is to develop a rapid and low-cost detection method for carbapenemase-producing Enterobacterales.
Developed a colorimetric assay called resaCPE.
Used an imipenem disk in combination with a cell viability assay.
Validated the assay with 116 isolates, comparing its performance against other detection methods.
resaCPE demonstrated a sensitivity of 98.7%.
Outperformed CARBA-NP (87.8% sensitivity) and mCIM (96.3% sensitivity).
Provided results within 3.5 hours with a specificity of 94.1%.

Cite This Study

Jeffs et al. (2026) studied this question.

synapsesocial.com/papers/69a3d856ec16d51705d2f09c https://doi.org/10.1128/jcm.01003-25

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Implication

Develops a rapid colorimetric assay to detect carbapenemase-producing Enterobacterales, suggesting it could improve infection control in healthcare.

resaCPE: a rapid, low-cost colorimetric assay for the detection of carbapenemase-producing Enterobacterales

Discussion

Member takes

Implication

Key Points

Cite This Study

resaCPE: a rapid, low-cost colorimetric assay for the detection of carbapenemase-producing Enterobacterales

Discussion

Member takes

Implication

Key Points

Cite This Study

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