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June 3, 2024Proceedings of the National Academy of SciencesOpen Access

Structure-based identification of a G protein–biased allosteric modulator of cannabinoid receptor CB1

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Authors

SSSiyuan ShenCWChao WuGLGuifeng Lin

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Shen et al. (2024) studied this question.

synapsesocial.com/papers/68e665f2b6db6435875f2277https://doi.org/10.1073/pnas.2321532121
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  3. 3Positive allosteric modulation of the cannabinoid CB<sub>1</sub> receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics2024 · 10 citations
  4. 4Essential Dynamics of CB<sub>1</sub>Receptor-Agonist Complexes: Implications for Signalling Bias2024 · 1 citations
  5. 5Structural basis for positive allosteric regulation of CB2 receptor2026