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October 8, 2025Frontiers in NeuroscienceOpen Access

Interaction between emotion lability, emotion regulation and structural brain abnormalities in patients with anorexia nervosa and borderline personality disorder

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Authors

MWMagdalena Wayda‐ZalewskaAPAgnieszka PlutaTWTomasz Wolak

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Overview

This analysis reports significant brain differences and challenges in emotion dysregulation in AN and BPD.

Key Points

  • Patients with anorexia nervosa show more adaptive emotion regulation compared to those with borderline personality disorder, especially in self-blame.
  • Structural MRI revealed significant differences in brain areas such as the prefrontal cortex and insula between clinical groups and healthy controls.
  • Higher emotional lability and reliance on maladaptive strategies were observed in borderline personality disorder patients compared to anorexia nervosa subjects.
  • Neurobiological findings suggest potential pathways for developing targeted interventions for emotion regulation in these disorders.

Cite This Study

Wayda‐Zalewska et al. (2025) studied this question.

synapsesocial.com/papers/68e6679587ecc93a24d17768https://doi.org/10.3389/fnins.2025.1545599
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Neural Underpinnings of Cognitive Reappraisal and Emotion Suppression in Response to Disorder‐Specific Stimuli in Women With Borderline Personality Disorder and Women With Restrictive Anorexia Nervosa: An fMRI Study2025
  2. 2EMOTION REGULATION PROFILING IN INDIVIDUALS WITH BORDERLINE PERSONALITY DISORDER COMPARED TO NON-CLINICAL SAMPLE2025
  3. 3Attentional mechanisms of borderline personality disorder2002 · 261 citations
  4. 4Neuroimaging insights into Borderline Personality Disorder patients with and without suicide attempts: A multi-modal structural MRI study.2026
  5. 5Assessment of neurotransmitter-related structural brain changes in borderline personality disorder: an MRI study2026