The mandible and maxilla can potentially develop central odontogenic fibromas (COF), an uncommon tumor of odontogenic origin with a variety of histopathologies. It can be challenging to diagnose; as a result, it is important to assess the clinical, radiographic, and histological studies of COF and correlate them in a way that facilitates the treating physician's ability to reach a conclusive diagnosis. Herein, we report and discuss the first known case of central odontogenic fibroma in our institute: a 52-year-old boy presenting as a hard-bony painless swelling of the left maxillary region. It appeared as a large, well-defined unilocular radiolucency on the CBCT, making it indistinguishable from other radiolucent tumors of the maxilla. Histologically, the lesion consisted of nests of odontogenic epithelium in between the fibroblastic stroma, confirming a definitive diagnosis of COF. It was treated by conservative surgical excision followed by curettage and no postoperative complications were reported.
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Jha et al. (2024) studied this question.
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