Central Odontogenic Fibroma in Mandible: Clinical Features, Diagnosis, and Surgical Approach

In this case report, the characteristics, diagnosis, and treatment approaches of central odontogenic fibroma, a very rare tumor, are described. A systemically healthy 29-year-old female patient was admitted to our clinic for routine checkups. Intraoral examination revealed a depression in the lingual gingiva of the right mandibular premolar region. Radiographic examination revealed a mixed, multilocular lesion in the right mandibular canine-premolar region with prominent cortical borders. Botryoid odontogenic cyst was considered in the differential diagnosis. A puncture biopsy of the lesion area was negative. With this finding, the lesion was thought to be a solid mass, and incisional biopsy was performed. On histopathologic examination, the lesion was diagnosed as central odontogenic fibroma. The lesion was excised under local anesthesia. After 18 months of follow-up, no recurrence was observed.