Polycystic Ovarian Syndrome and Endocrinological Disturbances: An Observational Study in A Tertiary Care Hospital of Bihar

Introduction: Polycystic ovary syndrome (PCOS) has emerged as one of the commonest endocrine disorders among females.It has been found to be associated with insulin resistance and hence increased risk to develop T2DM and CVS disorders along with endometrial carcinoma.The current study was planned to assess the metabolic and endocrine pattern of PCOS women at a tertiary care hospital of Bihar. Methodology:The present study was carried out in the department of Biochemistry, Darbhanga medical college, Laheriasarai The cases were selected from OPD of Obstetrics and Gynaecology department.The study population comprised of 60 women aged 15-50 years of age of diagnosed case of PCOS in study group.IEC approval was prior obtained. Results:It was observed that both serum FSH and LH was higher in the study group, although statistical significance was observed in case of serum LH.Serum insulin was also significantly higher in the study group.Similarly, a statistical significance was noted in blood profile of cases and control in terms of all the assessed parameters of thyroid profile. Conclusion:PCOS is not a reproduction dysfunction but a multi system malfunctioning affecting a major proportion of female population.Hence, timely therapeutic intervention can halt this ongoing process.