Opioid-Free Anesthesia in Transsphenoidal Surgery: A Case Report

Transsphenoidal surgery is a less invasive approach that leaves no visible scars, minimizes complications, and enables rapid recovery. The Enhanced Recovery After Surgery (ERAS) concept in neurosurgery aims to reduce hospitalization duration. Opioid-free anesthesia supports ERAS by reducing pain, postoperative nausea and vomiting (PONV), and shivering. This case series features women diagnosed with a suprasellar mass, who underwent transsphenoidal surgery with opioid-free anesthesia, achieving good outcomes through various agents and modalities for postoperative pain management. The operation proceeded with stable hemodynamics, underscoring the benefits of opioid-free anesthesia in supporting ERAS.