Evaluation of Serological Markers & Platelet Count in Dengue Infections in Pmch, Patna

Introduction- The dengue virus is arthropod borne virus-Arbovirous, belonging to family aviviridae and genus avivirus. It is a mosquito borne viral infection and is transmitted, primarily by Aedes aegypti and sometimes by Aedes albopictus. Dengue is caused by four distinct serotypes of viruses; DEN-1, DEN-2, DEN-3 AND DEN-4. Material and Method- 493 blood samples were taken from clinically suspected cases of dengue fever reporting at the hospital. Study was done from August 2022 to August 2023. Maximum number of patients were of age group 21-30 years and male: female ratio 3:1. The serum samples comprised of both acute and early convalescent phases depending on the reporting time of the patients. NS1 Ag assay in comparison to IgM- ELISAin acute or early convalescent sera was evaluated. Observtion (Result)-Atotal of 118 patient (out of 493) admitted in our hospital were diagnosed to have dengue. In October maximum no. of cases (52) were seen positive followed by September (39) cases were positive. This was followed by November (11) cases were positive. The present study included 30 (25%) female and 88 (75%) male patients