Activation of the hypoxia-inducible factor pathway by roxadustat improves glucose metabolism in human primary myotubes from men

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Roxadustat enhances inflammation and metabolic reprogramming in human leukocytes by affecting oxygen sensing.2025
2. 2Effect of Roxadustat on Cardiometabolism in Healthy Individuals (ROXACardioMeta): Protocol for a Double-Blind, Placebo-Controlled and Randomised Cross-Over Trial2026
3. 3Clinically approved HIF-PHIs modulate redox metabolism, cell growth, and angiogenesis independent of HIF-1α/HIF-2α2026
4. 4Exploring the potential application of roxadustat in chronic kidney disease-related osteoporosis based on the regulatory role of HIF-1α in bone metabolism.2026
5. 5Roxadustat improves diabetic myocardial injury by upregulating HIF-1α/UCP2 against oxidative stress2025 · 20 citations