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Abstract: Psoriasis is a long-term inflammatory skin condition that is thought to be caused by atypical proliferating keratinocytes that emerge in the form of substantial scaly, red, fragile patches. Although in current therapy, conventional treatments usually involve topical corticosteroids, immunosuppressants, and phototherapy, these therapies have restrictions and undesirable consequences. Nanotechnology provides significant novel opportunities for enhancing drug distribution and clinical effectiveness. The study focuses on a novel herb-based nanotechnological technique for treating psoriasis. The application of nanotechnology in herbal products has the potential to enhance the bioavailability, stability, and controlled administration of active substances, hence maximizing therapeutic outcomes and minimizing undesirable effects. Niosomes, liposomes, and nanoemulsions facilitate the penetration of herbal extracts such as aloe vera, turmeric, neem, and chamomile into the skin layers, along with providing anti-inflammatory, antioxidant, and immunomodulatory effects. This novel approach has the potential to strengthen therapeutic results, reduce adverse effects, and increase patient compliance. Also, the application of herbal extracts is consistent with the growing trend of natural and alternative healthcare treatments.
Patel et al. (Thu,) studied this question.